White matter hyperintensities on brain magnetic resonance in systemic sclerosis

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White matter hyperintensities on brain magnetic resonance in systemic sclerosis.

OBJECTIVE To evaluate the brain status of patients with systemic sclerosis (SSc). METHODS Fourteen female patients with SSc aged 24-74, with a disease duration of 1-12 years and without other relevant systemic diseases, were enrolled. All patients and an age matched female control group (CG) of 14 clinically normal subjects, underwent brain magnetic resonance examination at 1.5 T; spin echo p...

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A Hyperspectral Imaging Approach to White Matter Hyperintensities Detection in Brain Magnetic Resonance Images

White matter hyperintensities (WMHs) are closely related to various geriatric disorders including cerebrovascular diseases, cardiovascular diseases, dementia, and psychiatric disorders of elderly people, and can be generally detected on T2 weighted (T2W) or fluid attenuation inversion recovery (FLAIR) brain magnetic resonance (MR) images. This paper develops a new approach to detect WMH in MR b...

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Current concepts of analysis of cerebral white matter hyperintensities on magnetic resonance imaging.

Cerebrovascular disease is common and associated with cognitive deficits and increased risk for dementia. Until recently, only limited attention has focused on advances in imaging techniques to better define and quantify the spectrum of asymptomatic cerebrovascular disease commonly seen on magnetic resonance imaging, such as abnormal white matter signals. Abnormal signals in cerebral white matt...

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Retinal arteriolar geometry is associated with cerebral white matter hyperintensities on magnetic resonance imaging

BACKGROUND Cerebral small vessel disease (lacunar stroke and cerebral white matter hyperintensities) is caused by vessel abnormalities of unknown aetiology. Retinal vessels show developmental and pathophysiological similarities to cerebral small vessels and microvessel geometry may influence vascular efficiency. HYPOTHESIS Retinal arteriolar branching angles or coefficients (the ratio of the ...

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Genetic Determinants of White Matter Hyperintensities on Brain Scans

Background and Purpose—White matter hyperintensities (WMH) are highly heritable and associated with small artery ischemic stroke, so they may be a useful trait for studying the genetics of small vessel disease. Many studies have attempted to find associations between polymorphisms in various candidate genes and WMH. We aimed to evaluate the evidence for these associations by performing a system...

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ژورنال

عنوان ژورنال: Annals of the Rheumatic Diseases

سال: 2005

ISSN: 0003-4967

DOI: 10.1136/ard.2003.018283